Patients with coeliac disease given new hope with start of trial

“This trial is important in establishing clinical proof-of-concept for a treatment that would provide benefit beyond that of the gluten-free diet,” Dr Tye-Din said.

“The gluten-free diet is the only current treatment for coeliac disease but it is onerous, complex and not always effective.

“Even the most diligent patients can suffer the adverse effects of accidental exposure. This study will test if the vaccine, Nexvax2, can specifically target the immune response to gluten in people with coeliac disease and modify the associated effects.”